Coagulopathy, endothelial dysfunction, thrombotic microangiopathy and complement activation: potential role of complement system inhibition in COVID-19
نویسندگان
چکیده
منابع مشابه
Complement activation in thrombotic microangiopathy.
The endothelium lining the vascular lumen is continuously exposed to complement from the circulation. When erroneously activated on host cells, complement may generate a deleterious effect on the vascular wall leading to endothelial injury, exposure of the subendothelial matrix and platelet activation. In this review the contribution of complement activation to formation and maintenance of the ...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Thrombolysis
سال: 2020
ISSN: 0929-5305,1573-742X
DOI: 10.1007/s11239-020-02297-z